The coexistence of copy number variations (CNVs) and single nucleotide polymorphisms (SNPs) at a locus can result in distorted calculations of the significance in associating SNPs to disease.

TitleThe coexistence of copy number variations (CNVs) and single nucleotide polymorphisms (SNPs) at a locus can result in distorted calculations of the significance in associating SNPs to disease.
Publication TypeJournal Article
AuthorsLiu, J, Zhou, Y, Liu, S, Song, X, Yang, X-Z, Fan, Y, Chen, W, Akdemir, ZCoban, Yan, Z, Zuo, Y, Du, R, Liu, Z, Yuan, B, Zhao, S, Liu, G, Chen, Y, Zhao, Y, Lin, M, Zhu, Q, Niu, Y, Liu, P, Ikegawa, S, Song, Y-Q, Posey, JE, Qiu, G, Zhang, F, Wu, Z, Lupski, JR, Wu, N
Corporate AuthorsDISCO (Deciphering disorders Involving Scoliosis and COmorbidities) Study
PubMed ID30019117
PubMed Central IDPMC6200315
Grant ListR35NS105078 / / National Institute of Neurological Disorders and Stroke /
81472045 / / National Natural Science Foundation of China /
2016-I2M-2-006 / / CAMS Initiative Fund for Medical Sciences /
NINDS R01NS058529 / / National Institute of Neurological Disorders and Stroke /
xxjc201717 / / Beijing Nova Program Interdisciplinary Collaborative Project /
81772301 / / National Natural Science Foundation of China /
3332016006 / / PUMC Youth Fund & the Fundamental Research Funds for the Central Universities /
UM1 HG006542 / HG / NHGRI NIH HHS / United States
R35 NS105078 / NS / NINDS NIH HHS / United States
2016ZX310177 / / The Central Level Public Interest Program for Scientific Research Institute /
K08 HG008986 / HG / NHGRI NIH HHS / United States
NHGRI/NHLBI UM1 HG006542 / / National Human Genome Research Institute /
Z161100004916123 / / Beijing Nova Program /
PUMCH-2016-1.1 / / the 2016 PUMCH Science Fund for Junior Faculty /
81472046 / / National Natural Science Foundation of China /
JQ201506 / / the Distinguished Youth Foundation of Peking Union Medical College Hospital /
81501852 / / National Natural Science Foundation of China /
R01 NS058529 / NS / NINDS NIH HHS / United States
NHGRI K08 HG008986 / / National Human Genome Research Institute /
2016-I2M-3-003 / / CAMS Initiative Fund for Medical Sciences /
81772299 / / National Natural Science Foundation of China /
2017-I2M-2-001 / / CAMS Initiative Fund for Medical Sciences /
7172175 / / Beijing Natural Science Foundation /